#studies #research #news
The industrial doctorate offers a unique opportunity for companies, universities and doctoral students to work together.
22.05.2024
#open science #for society #news
On 11 June at 10:15 Sirelin Sillamaa will defend her doctoral thesis “The role of helicases Hmi1 and lrc3 in yeast mitochondrial DNA maintenance“ for obtaining the degree of Doctor of Philosophy (in Biochemistry).
17.05.2024
#open science #news
European Union’s Horizon EUROPE project A4L_BRIDGE has opened the first call for open access to Core Facilities.
08.05.2024
#for student #cooperation #studies #research #news
On 16 May, the Estonian Doctoral School Career Conference will be held in Tallinn to discuss the value of doctoral studies and the career prospects of doctoral students. All Estonian doctoral students and those interested in doctoral studies are welcome to attend.
07.05.2024

Future top-specialists of Estonian life sciences come from our Institute!

The Institute of Molecular and Cell Biology of the University of Tartu teaches the offspring of young researchers at all levels. Our researchers are at the top level in world-class science.

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MR Mikrokraad foto Reidar Andreson

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While studying and working at Estonian National University, we appreciate constant developing of Estonian scientific language accompanied by creation, elaboration and implementation of Estonian vocabulary in the particular scientific field.
28.09.2023

About Us

The Institute of Molecular and Cell Biology conducts research in molecular life sciences and provides "white biology" education at all three levels: bachelor's, master's and doctoral.
16.09.2021

New publications by IMCB's scientists:

Chair of Molecular Biology: RNA in ribosomes contains chemically modified nucleotides in addition to the normal ones. The existence and chemical structure of modified nucleotides have long been known, but their biological role remains a mystery. The study of biological functions is difficult because the absence of a single modification does not significantly alter the physiology of the cell or the function of ribosomes, these modifications are redundant. The novelty of our work lies in the use of a bacterial strain that lacks 10 genes determining modifications. The bacterial strain is viable, but only under very favourable conditions. By reintroducing into this strain one of the genes, of which the removal of one did not lead to significant changes, the bacterial growth and the ability to assemble ribosomes are significantly improved. By inserting genes back one by one, we determined which modifications are required for ribosome formation in E. coli cells. The results also help to clarify the redundancy of modifications, where several modifications can functionally replace each other.

Ribosomal RNA modification enzymes stimulate large ribosome subunit assembly in E. coli

Chair of Developmental Biology: To generate complex 3D organs, the shape of each cell needs to change to support the overall development of the tissue. Since these shapes are always changing, it is important to establish a protocol to monitor these changes as they happen in real time. In the developing wing of a fruit fly, Drosophila melanogaster, there are two layers of cells that are nearly identical and lie opposite each other. This study used live imaging to observe a network of cells that exists between these two layers, called the Interplanar Amida Network (IPAN). When this network loses its cell-to-cell contacts, it affects cell division in both layers, which is necessary for 3D tissue growth. This finding suggests that IPAN contributes to coordinating how tissues develop into 3D structures by changing cell shapes.

Programmed disassembly of a microtubule-based membrane protrusion network coordinates 3D epithelial morphogenesis in Drosophila

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Mobile Bioclass

The goal of the Mobile Bioclass is to introduce life sciences for schoolchildren and to increase their interest in biotechnology and related disciplines. 
13.05.2024

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MR LT-Tulf-359 (Mariana Tulf)

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