We have been studying the efficacy and mode of action of antimicrobial materials and coatings in cooperation with material scientists since 2015. The first project of the group that concerned antimicrobial materials ("In vitro toxicological tool-box for targeted design of antimicrobial nanomaterials”) aimed at finding of a set of effective microbicidal nanomaterials with minimal human hazard. The selected nanomaterials have a potential to be incorporated into a plastic matrix, or a polymer matrix, to be used as antimicrobial surface coatings. The results of this project were summarized in a popular science story.
Further development of antimicrobial coatings was carried out within two applied grants. In project “Novel antimicrobial surface coatings” we tested suitable matrices to which antimicrobial nanomaterials could be incorporated and another project “Development of antimicrobial surface coatings tested in real-life conditions into pilot production phase” focused on the development of matrices with an antimicrobial component to the production phase.
In addition to the development of antimicrobial materials and surfaces and their efficiacy testing we are also interested in studying the mechanisms of action of those materials as well as stress responses induced in bacterial cell.
Starting from 2020 the group has been involved in a project “Universal treatment method for antiviral protection of hard to clean surfaces” that focuses on antiviral materials and surfaces.
Header design: Aleksandr Käkinen
Rosenberg, Merilin; Visnapuu, Meeri; Saal, Kristjan; Danilian, Dmytro; Pärna, Rainer; Ivask, Angela; Kisand, Vambola (2021). Preparation and Characterization of Photocatalytically Active Antibacterial Surfaces Covered with Acrylic Matrix Embedded Nano-ZnO and Nano-ZnO/Ag. Nanomaterials. https://doi.org/10.3390/nano11123384
Malysheva, Anzhela; Ivask, Angela; Doolette, Casey L.; Voelcker, Nicolas, H.; Lombi, Enzo (2021). Cellular binding, uptake and biotransformation of silver nanoparticles in human T-lymphocytes. Nature Nanotechnology. https://dx.doi.org/10.1038/s41565-021-00914-3
Pietsch, Franziska; O’Neill, Alex J.; Ivask, Angela; Jenssen, Håvard; Inkinen, Jenni; Kahru, Anne; Ahonen, Merja; Schreiber, Frank (2020). Selection of resistance by antimicrobial coatings in the healthcare setting. Journal of Hospital Infection, 106 (1), http://dx.doi.org/10.1016/j.jhin.2020.06.006
Rosenberg, M.; Visnapuu, M.; Vija, H.; Kisand, V.; Kasemets, K.; Kahru, A.; Ivask, A. (2020). Selective antibiofilm properties and biocompatibility of nano-ZnO and nano-ZnO/Ag coated surfaces. Scientific Reports, 10 (1). http://dx.doi.org/10.1101/2020.03.18.996967
Rosenberg, Merilin; Azevedo, Nuno F.; Ivask, Angela (2019). Propidium iodide staining underestimates viability of adherent bacterial cells. https://doi.org/10.1038/s41598-019-42906-3
Rahmani, Ramin; Rosenberg, Merilin; Ivask, Angela; Kollo, Lauri (2019). Comparison of Mechanical and Antibacterial Properties of TiO2/Ag Ceramics and Ti6Al4V-TiO2/Ag Composite Materials Using Combined SLM-SPS Techniques. Metals, 9 (8), http://dx.doi.org/10.3390/met9080874
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Novaator: White cells help people tolerate the toxicity of nanosilver
Professor
Room 301, Riia 23, Tartu, 51010, Estonia
Phone: +372 737 5020 ; +372 5398298
Email: angela.ivask@ut.ee
PhD student, specialist
Room 304, Riia 23, Tartu, 51010, Estonia
Phone: +372 737 5020
Email: merilin.rosenberg@ut.ee
Sandra Vaikla
Student
Room 304, Riia 23, Tartu, 51010, Estonia
Phone: +372 737 5020
Levi Tomitsik
Student
Room 304, Riia 23, Tartu, 51010, Estonia
Phone: +372 737 5020