Topic: research

In the current project, we aim to uncover the role of aryl hydrocarbon receptor (AHR) in pancreatic ductal adenocarcinoma (PDAC). We test the hypothesis that inhibition of AHR activity with specific inhibitors has a potent therapeutic value in PDAC treatment. It is also important to mention that inhibition of AHR activity has great potential to boost the efficacy of cancer immunotherapy. Together with our project partners, we will develop and test novel AHR inhibitors in preclinical experiments.

On this page you will find a selection of the latest publications by our scientists

Current research and development projects

The Institute of Molecular and Cell Biology and former Estonian Biocentre, today Institute of Genomics, University of Tartu

On this page we will gather the information about all the defenses, still the relocation of the information from the former webpage will take some time.

We are interested in understanding the protein synthesis machinery in eukaryotes. The genetic information encoded in messenger RNA is translated into proteins by large ribonucleoprotein complex called

We are using efficient expression systems to produce heterologous proteins from pro- and eukaryotic organisms in Escherichia coli. We have expressed glucoside hydrolases (e.g. levansucrases, α-glucosi

Our research is focused on the response of microbial communities to anthropogenic and natural stressors in different environments. One of the main goals of our research is to determine the key microbial species and metabolic pathways responsible for the degradation of various hydrocarbon compounds of oil in different marine compartments (aerobic and anaerobic water, sediments and shoreline) of the Baltic Sea and Arctic marine environments.

We wish to understand how human genetic variation arose and diversified globally, as we know it today. It is an interdisciplinary research, where genetics & genomics mergers with history and archaeology, historical linguistics as well as data about paleoclimate etc. To achieve our goals, we co-organized, in the university, Collegium for Transdisciplinary Research in Archaeology, Genetics and Linguistics. Our chair works in historical symbiosis with the Estonian Biocentre within the Institute of Genomics and collaborates with many researchers worldwide.

Bacteria evolve rapidly under stress conditions where their growth is inhibited due to unfavorable growth conditions.