Topic: research

Bioinformatics research group

Our research is focused on the response of microbial communities to anthropogenic and natural stressors in different environments.

We are interested on the fundamental aspects of protein biosynthesis. In this respect we use E. coli as a model system. We study functional topography of the bacterial ribosome. In addition, we analyz

One of the key processes in the animal development is morphogenesis, the process by which the shape of tissues / organs is formed.

Our current research focus is the role of DNA copy-number changes in female reproductive ageing and infertility, chromosomal instability in human, and bovine as a model, early embryos. In addition development and implementation of new methods for transcriptomics, genome editing and epigenetic profiling of small number of cells to enable functional studies from well-defined cell populations including embryonic- and stem-cells.

Most bacteria live in biofilm, at least for some stage of life. We study the attachment of the cosmopolitan bacterium Pseudomonas putida, to the surface and the regulation of biofilm.

Survival and life of cells depend on accurate and faithful inheritance and expression of their genetic information in the course of DNA replication and gene transcription. These processes are highly regulated in multiple levels, including by the regulation of DNA accessibility in chromatin. The general aim of our research is to clarify the role of chromatin in regulation of these fundamental processes in eukaryotic cells.

The main focus of our research group is the development of disease models and new therapies based on the results of patient tissue analysis. Particular attention is paid to regeneration disorders (chr

The collection was initiated in 2018 when the research project "101 yeast strains from Estonian nature" took place. The project was carried out in collaboration with research teams led by Prof. Arnold Kristjuhan and Prof. Tiina Tamm.