Autor:
Jüri Parik

Külalisseminar: dr Kalle Rytkönen „Transcriptomic and steroidomic studies of the uterine endometrium and decidua“

9.11.2023 peab Omicumi maja auditooriumis nr 105 (Riia 23b/2) kell 16.00 külalisseminari Mariann Koeli doktoritöö oponent dr Kalle Rytkönen, Biomeditsiini Instituut, Turu Bioteaduste Keskus (Soome).

Seminari teema: Transcriptomic and steroidomic studies of the uterine endometrium and decidua

Kokkuvõte inglise keeles:

My research centers on the hormonal and genomic regulation of the uterine endometrium. We utilize recent single-cell data in combination with our in-house and previous transcriptomic data related to endometrial disorders. Our goal is to elucidate the contributions of specific cell types in the context of endometrial functions and disorders. The range of conditions we investigate includes endometriosis, adenomyosis, heavy menstrual bleeding, as well as pregnancy disorders such as preeclampsia. Additionally, we are conducting an analysis that links matched steroid levels with the transcriptomic activity of the enzymatic steroidogenesis machinery. This analysis will provide a more detailed understanding of the mechanisms responsible for intratissue steroid levels.

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