Geenitehnoloogia Talveseminar 2025
Author:
Andres Ainelo
Geenitehnoloogia Talveseminaril kohtusid Tartu ja Tallinna geenitehnoloogid
30.–31. jaanuarini toimus Jäneda mõisas Geenitehnoloogia Talveseminar, mis tõi kokku ligi 80 Tallinnas ja Tartus geenitehnoloogia erialadel tegutsevat kraadiõppurit ning teadlast. Kaks päeva sisustati ülevaadetega eri instituutides tehtavast teadustööst.
Seminarile olid kutsutud magistrandid, doktorandid ja juhendajad Tartu Ülikooli molekulaar- ja rakubioloogia instituudist ning Tallinna Tehnikaülikooli keemia ja biotehnoloogia instituudist. Avamisel rõhutas molekulaarbioloogia professor Tiina Tamm kahe instituudi vahelise koostöö olulisust.
Enda teadusprojektidest tegid ettekandeid 27 doktorant-nooremteadurit, uurimissuundadest rääkisid laiemalt nende juhendajad Tartus ja Tallinnas. Seminarile olid külalislektoriteks kutsutud professorid Patrick Pausch ja Steven Knox Jones Vilniuse Ülikooli alla kuuluvast asutusest LSC-EMBL Partnership for Genome Editing Technologies.
Mind motiveerib väga see, et saame teineteisega oma töö tulemusi ja tulevikuvaateid jagada. See avardab silmaringi. Mitte kuskilt mujalt ei saa sellist ülevaadet kõikidest uurimisrühmadest, nii mujalt kui ka mu enda instituudist.
Geenitehnoloogia Talveseminari korraldajad olid TÜ molekulaar- ja rakubioloogia instituudist Hedvig Tamman, Andres Ainelo ja Tiina Tamm ning Tallinna Tehnikaülikoolist Cecilia Sarmiento, Eve-Ly Ojangu ja Indrek Koppel. Seminar korraldati projekti „Ülikoolide koostöö doktoriõppe edendamisel“ (2021-2027.4.04.24-0003) raames. Projekti kaasrahastab Euroopa Liit.
Esinejad ja toimunud ettekanded
- Margus Leppik, PhD, UT. “Modifications of ribosomal RNA in bacteria and yeast”
- Analiis Veeremaa, UT. “The role of the eukaryote-specific intersubunit bridges in the regulation of viral IRES-mediated translation of the budding yeast ribosome”
- Indrek Koppel, PhD, TalTech. “Studying protein synthesis in the nervous system”
- Karl Jürgenstein, UT. “The impact of translational fidelity errors on mutation frequency in Pseudomonas putida strains with mutations in ribosomal protein S5”
- Riho Teras, PhD, UT. “Construction of reporter plasmids for oppositely transcribed genes”
- Johanna Hendrikson, UT. “Constructing a Dual-Reporter Plasmid: Investigating the Effect of Gene Orientation on Expression”
- Mia-Lota Keskküla, UT. “Choosing a pair of fluorescent proteins to use in a dual-reporter plasmid in P. putida”
- Anastassia Šubina, TalTech. “Insights into the interactome of transcription factor 4, a schizophrenia- and autism-associated basic helix-loop-helix transcription factor”
- Triin Vahisalu, PhD, TalTech. “Translational Plant Biology: Gene editing by CRISPR/Cas in crops. Barley – as an example”
- Irina Česnokova, TalTech. “Super-resolution imaging of maturing cardiomyocytes”
- Sigrid Kirss, TalTech. “World needs a Magic Bullet for Alzheimer's Disease”
- Agne Velthut-Meikas, PhD, TalTech. “Using transcriptomics to understand ovarian functions in health, disease and unfavourable environmental conditions”
- Inge Varik, TalTech. “Molecular Composition and Differential Effects of Human Follicular Fluid Extracellular Vesicle Subtypes on the Human Granulosa-Like Tumor Cell Line KGN”
- Guest speaker: Patrick Pausch, PhD (LSC-EMBL Partnership for Genome Editing Technologies, Vilnius University - Life Sciences Center). “Mechanism of a DNA producing and tRNA cutting bacterial immune system”
- Rita Hõrak, PhD, UT. “Arms race between bacteria and phages”
- Alicja Cecylia Lewańczyk, UT. “The TOL plasmid pWW0 in phage defense of Pseudomonas putida”
- Annika Rähni, TalTech. “Antibody Response Patterns in Psychosis Spectrum Disorders: Investigating Antibody-Epitope Signatures Using Phage Display and Next Generation Sequencing”
- Triinu Visnapuu, PhD, UT. “Synergistic effects of polysaccharides and plant-derived bacteria in promoting plant health”
- Giuseppe Leonardo Auditano, TalTech. “Bioenergetic Pathways in Colon Cancer: Investigating Glycolytic Flux and Enzyme Kinetics in Clinical Samples and Caco-2 Cells.”
- Naatan Seeba, TalTech. “A negatively charged cluster in the disordered acidic domain of GPIHBP1 provides selectivity in the interaction with lipoprotein lipase”
- Kannan Thirumal Muthu, TalTech. “Microbial Utilization of Technical Lignins”
- Maarja Lipp, TalTech. “New insights into the structure and mechanisms of different lytic polysaccharide monooxygenases”
- Darja Vastšjonok, UT. “Redox enzymes in removal of phenolic compounds from wastewater streams of shale oil production”
- Guest speaker Stephen Jones, PhD (EMBL Partnership Institute at the Vilnius University Life Sciences Center). “How precise is precise? Pursuing specific editing outcomes with CRISPR nucleases”
- Annely Lorents, PhD, UT. “Developing drug delivery strategies for RNA-based therapeutics”
- Syed Shahid Musvi, TalTech. “Identification of the new replication initiation factors in human cells”
- Sameera Vipat, TalTech. “The role of TIMELESS protein in DNA replication initiation in human cells”
- Juliano Sabedotti De Biaggi, TalTech. “Valorizing Waste with Gene Tech”
- Helena Tull, TalTech. “Molecular communication between neurons and glia”
- Laura Luhari, TalTech. “Integrative multi-omics analyses of clinical outcomes in lung adenocarcinoma”
- Carl Sander Kiir, TalTech. “Genome-Wide Characterization of Neuronal Activity-Dependent Transcription in Drosophila”
- Age Brauer, PhD, UT. “Small packages, big impact: the power of compact phage genomes”
- Alīna Reķēna, TalTech. “Computational design of yeast-based cell factories”
- Angela Ivask, PhD, UT. “Benefits of antimicrobial surface coatings but what about threats?”
- Sandra Park, UT. “Natural transformation of Escherichia coli on antimicrobial surfaces”
- Laura Kaarma, TalTech. “Design and development of antifungal materials for biomedical applications”
- Lea Ets, UT. “Mechanisms affecting fluoride tolerance in soil bacteria Pseudomonas putida”
- Dániel Kácsor, TalTech. “Microfluidic image analysis: turning droplets into numbers”
- Ilona Juvonen, TalTech. “Metal-phenolic network-coated nanoparticles for sustainable metal recycling”
Loe veel sarnaseid uudiseid
18.02.2025
